They found that both cannabinoids potentiated the extinction of cocaine- and amphetamine-induced place preference learning and that this effect was not reversed by the administration of a CB1 receptors antagonist. These effects were not mediated by learning or retrieval alteration and CBD did not have hedonic properties on its own. Moreover, they also studied the effects of cannabinoids on the establishment of stimulant CPP. The effects of CBD were examined during the maintenance and extinction phases of SA and during cue-induced reinstatement. On the other hand, CBD failed to influence drug-seeking behavior initiated by heroine prime.

• A 2013 report published in Neuropsychopharmacology described the case of a 19-year-old woman who had cannabis withdrawal symptoms.
• And, while there is a lot of positive talk about cannabis, there are risks—especially if you’re over 55.
• This can lead to intense cravings for drugs and an inability to resist using them 3.
• As the popularity of CBD continues to grow, reaching every corner of the world, people start asking more and more questions about its properties — including possible downsides.

Effects of CBD on psychostimulant-addictive behaviors

• One study found that CBD reduced craving and anxiety in individuals with cannabis use disorder.
• Start with a low dose of 5-10mg once daily and gradually increase if needed.
• Poor sleep is often linked to anxiety and pain – two conditions CBD may help address simultaneously.
• This particular study suggests individuals with drug addiction may benefit from EPIDIOLEX, the FDA-approved CBD addiction medicine.

Ren et al studied the postmortem brain of rats and found that CBD normalized the heroin-induced changes in CB1 receptor mRNA expression and AMPA GluR1 in the nucleus accumbens, even after 2 weeks of treatment. More studies are needed to clarify the exact mechanisms through which CBD influences addictive behaviors, in addition to the endocannabinoid, glutamatergic, and serotoninergic systems. These mechanisms may well be different for each substance of abuse and each addictive phase. The U.S. Food and Drug Administration (FDA) plays a crucial role in regulating CBD products. The only FDA-approved CBD-based medication is cannabidiol addictive is called Epidiolex for the treatment of severe forms of epilepsy. However, the FDA has not approved CBD for other uses, such as mental health conditions, chronic neuropathic pain management or substance use disorders.

Meet our medical team

• The studies that showed negative results provided either a single dose of CBD 56 or included chronic schizophrenia patients who received multiple types of antipsychotic medication 57.
• Sometimes spotting addictive behaviors in individuals can be difficult, but learning how to recognize the signs can help you or your loved ones get the help they need sooner.

As a result, cannabidiol doesn’t trigger the intoxicating psychoactive effects of THC. But early data suggests CBD also can reduce feelings of tension or stress. Misinformation surrounding CBD often fuels myths about its addictive nature. One common misconception links all cannabis-derived products to dependency, failing to account for the significant differences between THC and CBD. While THC binds to CB1 receptors in the brain – causing psychoactive effects, CBD has no such impact.

• While CBD does not appear to be addictive and may have some benefits, one large-scale review concluded that there was not enough evidence to support the use of CBD as a treatment for mental health conditions.
• The potential addictiveness of CBD products boils down to guilt by association.
• This 2021 study (2) reports that CBD may even help reduce cravings in patients recovering from drug abuse.
• Addiction experts estimate that 91% of marijuana users never become problematic, meaning that 9% will form improper habits around the use of the plant, which may generate some form of abuse.
• This is especially true regarding drugs such as MDMA, cocaine, or crack that exert most of its effects through the dopamine system.

Medical Marijuana: Facts about cannabis, THC, and CBD

This article investigates whether or not you can get addicted to CBD, and we’ll also touch on the concepts behind drug and alcohol dependence and the general safety of CBD products on the market. Leafy Mate is a platform dedicated to assisting users in navigating the cannabis industry. We provide an exceptional experience by helping users discover their favorite products and brands, locate local dispensaries, and connect with the right medical professionals.